Updates to Chemical Effects in Biological Systems (CEBS)

In the past quarter, the National Toxicology Program (NTP) has released data gathered on the long-term effects of radio frequency radiation at modulations used by some cell phones. Searching for “cell phone radiation” in the CEBS interface now returns all related data gathered for CDMA and GSM modulations. Types of data available include 28-day and chronic toxicity studies in rats and mice, as well as micronucleus and DNA damage genetic toxicology data. Data from these studies can be found within the CEBS Histopathology, CEBS Gross Pathology Observation Data, CEBS In-Life Observation Data, and CEBS Genetic Toxicity: Micronucleus Data domains.

CEBS has also made updates to the CEBS Developmental Data domain. Data from legacy Developmental and Reproductive Toxicity (DART) evaluations from 1985 to 2005 are available in the NTP Legacy Data folder. These data are available as single spreadsheet that contains data for 98 test articles and endpoints such as estrus cyclicity, sperm parameters, pregnancy and litter effects, developmental markers (vaginal opening, preputial separation, testes descent) and fetal examination. These studies were conducted by a contract laboratory for the NTP and the findings may or may not have been peer reviewed. Findings and conclusions in the DART dataset should not be construed to represent the views of the NTP or the U.S. Government.

CEBS has recently updated its technology platform and search algorithms to improve the user experience (https://manticore.niehs.nih.gov/cebssearch/). The new interface offers a single search bar and faceted filtering of results to simplify querying the dataset. All data for a single test article or NTP report are displayed on a single page.