U.S. Government Monkeypox Research Summary

The U.S. Government, in partnership with State, local, and expert stakeholders have identified critical areas of research that will advance our understanding of the U.S. and global monkeypox outbreak and enable us to effectively respond to the current outbreak as well as prevent future outbreaks.

The table below outlines near-term (planned) and ongoing projects led by U.S. Government agencies including National Institutes of Health (NIH) and its components National Institute of Allergy and Infectious Diseases (NIAID) and National Institute of Biomedical Imaging and Bioengineering (NIBIB); U.S. Centers for Disease Control and Prevention (CDC); Department of Defense (DOD) including its components Defense Threat Reduction Agency (DTRA), Walter Reed Army Institute of Research (WRAIR), U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID), Naval Medical Research Center (NMRC), Naval Research Laboratory (NRL), Defense Advanced Research Projects Agency (DARPA), Joint Science and Technology Office (JSTO), and Joint Program Executive Office (JPEO); Department of Veterans Affairs (VA) and its components Veterans Health Administration (VHA), with the Armed Forces Health Surveillance Division (AFHSD)/Defense Health Affairs (DHA); Department of State (DOS) and its components Office of the Global AIDS Coordinator (S/GAC), Bureau of International Security and Nonproliferation (ISN); and Department of Energy (DOE).

Note, research studies are influenced by numerous factors that can shift throughout a response, e.g., the ability to accrue patients for a clinical trial can substantially impact completion dates. As such, the Department of Health and Human Services (HHS) and the agencies leading the projects below will make every effort to update the completion dates as new information becomes available. As we make progress against these research efforts and our understanding of the Monkeypox virus and this outbreak evolve, this table will be updated periodically.